简　　历：

博士，教授，获国家“优秀青年基金”资助。2014年于中国科学技术大学获得博士学位。主要从事环境生物技术方面的研究工作，在水污染控制技术的研发、化学品绿色制造的合成生物学研究、下一代分子诊断技术的环境应用等方面进行了深入系统的研究。以第一/通讯作者在Nature Communications（2篇）、Environmental Science and Technology（13篇）、Environmental Science & Technology Letters （2篇）、Water Research、Nucleic Acids Research、Metabolic Engineering、Environmental Microbiology（2篇）、Biotechnology and Bioengineering（6篇）、ACS Synthetic Biology（3篇）等刊物上发表论文40余篇，获教育部自然科学一等奖（2022年）。任ISME Communications的编委，Frontiers of Environmental Science & Engineering青年编委。

获奖及荣誉：

1. 教育部自然科学一等奖（2022年）

2. 安徽省研究生教学成果奖二等奖（2022年）

3. 国家优青（2023年）

4. 安徽省杰青（2022年）

代表性论著：

1.       Zhou-Hua Cheng#, Xi-Yan Luo#, Sheng-Song Yu#, Di Min, Shu-Xia Zhang, Xiao-Fan Li, Jie-Jie Chen, Dong-Feng Liu*, Han-Qing Yu*, Tunable Control of Cas12 Activity Promotes Universal and Fast One-Pot Nucleic Acid Detection, Nature Communications, 2025, 16(1):1166

2.       Lan Hu, Jing Han, Hao-Da Wang, Zhou-Hua Cheng*, Chang-Ce Lv, Dong-Feng Liu*, Han-Qing Yu*, A Universal and Wide-Range Cytosine Base Editor via Domain-Inlaid and Fidelity-Optimized CRISPR-FrCas9, Nature Communications, 2025, 16(1):1260

3.       Cheng Zhou-Hua; Yu Han-Qing; Liu Dong-Feng*, Making CRISPR-Dx Technology Work in Environmental Monitoring, Environmental Science & Technology, 2025, In press

4.       Cheng, Zhou-Hua#; Luo, Xi-Yan#; Liu, Dong-Feng*; Han, Jing; Wang, Hao-Da; Min, Di; Yu, Han-Qing*, Optimized Antibiotic Resistance Genes Monitoring Scenarios Promote Sustainability of Urban Water Cycle, Environmental Science & Technology, 2024, 58(22): 9636-9645

5.       Wu Jing; Lv Yun-Hui; Sun Dan; Zhou Jun-Hua; Wu Jie; He Ru-Li; Liu Dong-Feng*; Song Hao; Li Wen-Wei*, Phthalates boost natural transformation of extracellular antibiotic resistance genes through enhancing bacterial motility and DNA environmental persistence, Environmental Science & Technology, 2024, 58(17): 7291-7301

6.       Di Min, Dong-Feng Liu*, It Is Time to Explore Unique Mechanisms for Microbial Antimony Conversion Rather Than Relying on Analogies with Arsenic Bioconversion, Environmental Science & Technology, 2023, 57(42):15780-15781

7.       Yuan Pan, Dong-Feng Liu*, Tapping the Potential of Wastewater Treatment with Direct Ammonia Oxidation (Dirammox), Environmental Science & Technology, 2023, 57(18): 7106-7108

8.       Jing Wu; Jun-Hua Zhou; Dong-Feng Liu*; Jie Wu; Ru-Li He; Zhou-Hua Cheng; Hui-Hui Li; Wen-Wei Li*, Phthalates Promote Dissemination of Antibiotic Resistance Genes-An Overlooked Environmental Risk, Environmental Science & Technology, 2023, 57(17): 6876-6887

9.       Di Min; Lei Cheng; Dong-Feng Liu*; Jia-Qi Liu; Wen-Wei Li; Han-Qing Yu*, Single Strain-Triggered Biogeochemical Cycle of Arsenic, Environmental Science & Technology, 2022, 56, 22, 16410–16418.

10.   Ru-Li He; Jie Wu; Zhou-Hua Cheng; Hui-Hui Li; Jia-Qi Liu; Dong-Feng Liu*; Wen-Wei Li*, Biomolecular Insights into Extracellular Pollutant Reduction Pathways of Geobacter sulfurreduences using Base Editor System, Environmental Science & Technology, 2022, 56, 17, 12247–12256.

11.   Di Min; Lei Cheng; Jia-Qi Liu; Dong-Feng Liu*; Wen-Wei Li; Han-Qing Yu*; Ligand-assisted formation of soluble Mn(III) and bixbyite-like Mn2O3 by Shewanella putrefaciens CN32, Environmental Science & Technology, 2022, 56(6), 3812–3820.

12.   Jie Wu; Zhou-Hua Cheng; Di Min; Lei Cheng; Ru-Li He; Dong-Feng Liu*; Wen-Wei Li*; CRISPRi System as an Efficient, Simple Platform for Rapid Identification of Genes Involved in Pollutant Transformation by Aeromonas hydrophila, Environmental Science & Technology, 2020, 54(6), 3306-3315.

13.   Lei Cheng; Di Min; Dong-Feng Liu*; Wen-Wei Li; Han-Qing Yu*; Sensing and Approaching Toxic Arsenate by Shewanella putrefaciens CN-32, Environmental Science & Technology, 2019, 53(24), 14604-14611

14.   Di Min#; Lei Cheng#; Feng Zhang; Xue-Na Huang; Dao-Bo Li; Dong-Feng Liu*; Tai-Chu Lau; Yang Mu; Han-Qing Yu*; Enhancing Extracellular Electron Transfer of Shewanella oneidensis MR-1 through Coupling Improved Flavin Synthesis and Metal-Reducing Conduit for Pollutant Degradation, Environmental Science & Technology, 2017, 51(9), 5082-5089

15.   Yi-Nan Liu#; Feng Zhang#; Jie Li; Dao-Bo Li; Dong-Feng Liu*; Wen-Wei Li; Han-Qing Yu*; Exclusive Extracellular Bioreduction of Methyl Orange by Azo Reductase-Free Geobacter sulfurreducens, Environmental Science & Technology, 2017, 51(15), 8616-8623

16.   Lei He and Dong-Feng Liu*, Emerging Challenges and Future Directions in Insect-Mediated Plastic Degradation，Environmental Science & Technology Letters, 2024, 11, 5, 394-396

17.   Jun-Cheng Han#; Feng Zhang#; Lei Cheng; Yang Mu; Dong-Feng Liu*; Wen-Wei Li; Han-Qing Yu; Rapid Release of Arsenite from Roxarsone Bioreduction by Exoelectrogenic Bacteria, Environmental Science & Technology Letters, 2017, 4(8), 350-355

18.   Zhou-Hua Cheng, Ji Li, Hui Zhang, Dong-Feng Liu*, Han-Qing Yu*, Influent, As Opposed to Activated Sludge, Is More Suitable for SARS-CoV-2 Surveillance in Wastewater Treatment Plants, Water Research, 2025, 273:123038

19.   Zhou-Hua Cheng; Jie Wu; Jia-Qi Liu; Di Min; Dong-Feng Liu*; Wen-Wei Li*; Han-Qing Yu*, Repurposing CRISPR RNA-Guided Integrases System for One-Step, Efficient Genomic Integration of Ultra-Long DNA Sequences, Nucleic Acids Research, 2022, 50(13), 7739–7750.

20.   Jie Wu#, Jing Wu#, Ru-Li He, Lan Hu, Dong-Feng Liu**, Wen-Wei Li**, Modularized Engineering of Shewanella oneidensis MR-1 for Efficient and Directional Synthesis of 5-Aminolevulinic Acid, Metabolic Engineering, 2024, 83: 206-215  

21.   Ting-Ting Zhu#, Zhou-Hua Cheng#, Sheng-Song Yu, Wen-Wei Li, Dong-Feng Liu*, Han-Qing Yu*; Unexpected role of electron-transfer hub in direct degradation of pollutants by exoelectrogenic bacteria, Environmental Microbiology, 2022, 24(4), 1838-1848

22.   Jie Wu, Dong-Feng Liu*, Hui-Hui Li, Di Min, Jia-Qi Liu, Peng Xu, Wen-Wei Li*, Han-Qing Yu, Yong-Guan Zhu; Controlling pathogenic risks of water treatment biotechnologies at the source by genetic editing means, Environmental Microbiology, 2021, 23(12), 7578-7590 

承担科研项目情况：

1. 国家自然科学基金委员会, 青年科学基金项目（B类）[原优秀青年科学基金项目], 52322002, 水污染控制, 2024-01-01 至 2026-12-31, 200万元, 在研, 主持

2. 国家自然科学基金委员会, 面上项目, 51878638, 城市污水处理厂活性污泥中地杆菌分布特征和作用机制的研究, 2019-01-01 至 2022-12-31, 61万元, 结题, 主持

3. 国家自然科学基金委员会, 青年项目, 21607146, 希瓦氏菌对环境污染物类胞外电子受体的趋化响应机制研究 2017-01-01 至 2019-12-31, 21万元, 结题, 主持